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Arginine metabolism during macrophage autocrine activation and infection with mouse hepatitis virus 3

✍ Scribed by Cristiani Moreira; Maria H. Tsuhako; Milene Tino de Franco; Manuel Modolell; Carlos A. Pereira


Book ID
116569022
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
601 KB
Volume
209
Category
Article
ISSN
0171-2985

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## Abstract Signal transducer and activator of transcription 1Ξ± (STAT1 Ξ±) is reported to be essential for IFN‐γ and IFN‐α regulated gene expression, while STAT1 Ξ², an alternate splice‐form, mediates only IFN‐α‐dependent gene expression. STAT3 Ξ± and STAT3 Ξ² splice forms are also differentially activ