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Arginine deiminase, a potential anti-tumor drug

โœ Scribed by Ye Ni; Ulrich Schwaneberg; Zhi-Hao Sun


Book ID
116334610
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
630 KB
Volume
261
Category
Article
ISSN
0304-3835

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In vivo anti-tumor activity of arginine
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Arginine deiminase (EC 3.5.3.6) was purified to homogeneity from the cell extract of Mycoplasrno arginini by molecular-sieve, anion-exchange and arginine-affinity chromatographies. The purified enzyme was composed of 2 identical sub-units with a molecular weight of 45.000 and had a pl of 4.7. Its V,