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Arginine 490 is a hot spot for mutation in the band 3 gene in hereditary spherocytosis

✍ Scribed by Paulo Roberto Moura Lima; Teresa Sueko Ide Sales; Fernando Ferreira Costa; Sara Teresinha Olalla Saad


Book ID
114792507
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
214 KB
Volume
63
Category
Article
ISSN
0902-4441

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## Abstract Hepatoblastomas generally appear in children aged 2 or 3 years old and arise from apparently normal, noncirrhotic liver. To elucidate any possible role of p53 mutations in their genesis, we amplified and sequenced exons 5 to 8 of the p53 gene in 10 cases of hepatoblastoma. Somatic mutat