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ARGINASE INHIBITION SUPPRESSES BLADDER OVERACTIVITY IN RATS WITH CHRONIC SPINAL CORD INJURY BY ENHANCING NO PRODUCTION

✍ Scribed by Sasatomi, Kurumi; Hiragata, Shiro; Miyazato, Minoru; Chancellor, Michael B; Morris, Sidney M; Yoshimura, Naoki

Book ID: 122486302
Publisher: Lippincott Williams and Wilkins
Year: 2008
Tongue: English
Weight: 136 KB
Volume: 179
Category: Article
ISSN: 0022-5347
DOI: 10.1016/S0022-5347(08)61023-X

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## Abstract It is well established that axons of the adult mammalian CNS are capable of regrowing only a limited amount after injury. Astrocytes are believed to play a crucial role in the failure to regenerate, producing multiple inhibitory proteoglycans, such as chondroitin sulphate proteoglycans