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Are thrombocytes and platelets true phagocytes?

✍ Scribed by José Meseguer; M. Ángeles Esteban; Alejandro Rodríguez

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
74 KB
Volume
57
Category
Article
ISSN
1059-910X

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✦ Synopsis

Thrombocytes and platelets, beyond their primary function in hemostasis, seem to play an active role in inflammation. As regards their phagocytic ability, the results to date are confusing, incomplete, and somewhat contradictory. Whereas the interaction of avian thrombocytes or mammalian platelets with bacteria both in vitro and in vivo has received wide attention, almost no information exists on the topic in "lower" vertebrates. The aim of this work is to review the available information on the phagocytic properties of thrombocytes and platelets. Particular attention is payed to the ontogeny of these cells, the soluble factors involved in the inflammatory process derived from them, and their interaction with particulate material, mainly with bacteria.

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