Are phospholipases involved in platelet activation?
✍ Scribed by G. Bereziat
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1979
- Tongue
- English
- Weight
- 820 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1420-908X
No coin nor oath required. For personal study only.
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## Abstract Human preimplantation embryos secrete platelet‐activating factor (PAF), which stimulates prostaglandin E~2~ synthesis from secretory endometrium. This study investigated the action of PAF on phosphatidylinositol 4,5‐bisphosphate (Ptdlns(4,5)P~2~)‐specific phospholipase C activity in hum
Phospholipase D (PLD) is stimulated in platelets by various agents. Phosphatidylcholine is the major substrate for PLD. This enzymatic pathway generates phosphatidic acid selectively. Guanine nucleotides also stimulate PLD in platelet membranes. Furthermore, tyrosine kinase may also be involved in p