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Are hydantoins (phenytoins)human teratogens?

โœ Scribed by Samuel Shapiro; Dennis Slone; Stuart C. Hartz; Lynn Rosenberg; Victor Siskind; Richard R. Monson; Allen A. Mitchell; Olli P. Heinonen


Book ID
119455786
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
209 KB
Volume
90
Category
Article
ISSN
1097-6833

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## Abstract We have recently demonstrated that phenytoin, a widely used therapeutic agent for seizure disorders, has osteogenic effects in rats and in humans in vivo, and in human bone cells in vitro. The goal of the present study was to determine the mechanism of the osteogenic action of phenytoin