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Are behavioral syndromes of schizophrenia associated with allelic variations of the tyrosine hydroxylase gene?

✍ Scribed by J. Wei; G.P. Hemmings


Book ID
119560040
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
99 KB
Volume
29
Category
Article
ISSN
0920-9964

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Systematic search for variations in the
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Tyrosine hydroxylase is the rate-limiting step in the biosynthesis of catecholamines. To find variants in the tyrosine hydroxylase (TH) gene that are associated with schizophrenia, mood disorders, or alcohol dependence, all of the exons, the exon-intron boundaries, and the 5 promoter region of the T

Association study of structural mutation
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Tyrosine hydroxylase (TH) gene is the ratelimiting enzyme in the synthesis of catecholamines. Functional polymorphisms of the TH gene may be involved in the pathogenesis of neuropsychiatric diseases such as schizophrenia, affective disorders, and Parkinsonism. This study examined a possible associat