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ARDent about acetylation and deacetylation in hypoxia signalling

✍ Scribed by Rebecca Bilton; Eric Trottier; Jacques Pouysségur; M. Christiane Brahimi-Horn

Book ID
113926053
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
298 KB
Volume
16
Category
Article
ISSN
0962-8924

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Histone acetyltransferases and deacetylases can be targeted to promoters to activate or repress genes. For example, the histone acetyltransferase GCN5 is part of a yeast multiprotein complex that is recruited by the DNA-binding activator protein GCN4 (refs 1-3). The histone deacetylase RPD3 complex