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Architectural (FIGO) grading, nuclear grading, and other prognostic indicators in stage I endometrial adenocarcinoma with identification of high-risk and low-risk groups

✍ Scribed by Khushbakhat R. Mittal; Peter E. Schwartz; Kenneth W. Barwick


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
996 KB
Volume
61
Category
Article
ISSN
0008-543X

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✦ Synopsis


We studied 164 cases of Stage I endometrial adenocarcinoma to determine the relative prognostic value of International Federation of Gynecology and Obstetrics (FIGO) and nuclear grading systems. Other factors known to be of prognostic value in endometrial carcinoma also were evaluated. Both the FIGO and nuclear grading systems correlated with five-year mortality rate from cancer. Nuclear Grade 3 proved to be a superior predictor of fatal outcome (nine of 13 169761) over FIGO Grade 3 (four of 13 13181). We advocate the combined use of FIG0 and nuclear grading systems, along with other prognostic parameters, for the detection of most patients with fatal cancer.