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Arachidonic and docosahexaenoic acids reduce the growth of A549 human lung-tumor cells increasing lipid peroxidation and PPARs

✍ Scribed by Antonella Trombetta; Marina Maggiora; Germana Martinasso; Paolo Cotogni; Rosa A. Canuto; Giuliana Muzio


Book ID
113517483
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
695 KB
Volume
165
Category
Article
ISSN
0009-2797

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## Abstract The type 1 insulin-like growth factor receptor (IGF-1R), which is over-expressed or activated in many human cancers, including lung cancer, mediates cancer cell proliferation and metastasis. Several studies indicate that blocking IGF-1R expression can inhibit tumor cell proliferation an