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Arachidonic acid release induced by LPS in microglial cells

✍ Scribed by Cecilia Guastadisegni; Maria Balduzzi; Alessia Nicolini; Luisa Minghetti


Book ID
114101197
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
73 KB
Volume
59
Category
Article
ISSN
0090-6980

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The effect of cannabinoids on the induction of cytokine mRNA by rat microglial cells was examined. Exposure of neonatal rat cortical microglial cells to the exogenous cannabinoid ␦ 9 -tetrahydrocannabinol (THC) resulted in reduced amounts of lipopolysaccharide (LPS)-induced mRNAs for IL-1␣, IL-1␀, I