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Arachidonic acid metabolism in cultured aortic endothelial cells: Effect of cAMP and 3-isobutyl-1-methylxanthine

✍ Scribed by A.Richard Whorton; James B. Collawn; Malcolm E. Montgomery; Stephen L. Young; Richard S. Kent

Book ID
115778056
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
663 KB
Volume
34
Category
Article
ISSN
0006-2952

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Incubation of cultured bovine pulmonary artery endothelial cells with 200 pM of 3-isobutyl-1 -methylxanthine (IBMX) for 24 hr produced a five-to tenfold increase in cellular angiotensin converting enzyme activity (ACE) above that of untreated control cells. A lesser increase was observed in medium A