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ARACHIDONIC ACID METABOLISM AND MODULATION OF in vitro ANAPHYLAXIS BY 5,8,11,14-EICOSATETRAYNOIC ACID AND 9a,12a-OCTADECADIYNOIC ACID

✍ Scribed by MARGARET HITCHCOCK; NICHOLAS A. KOKOLIS

Book ID
117957619
Publisher
Nature Publishing Group
Year
1981
Tongue
English
Weight
960 KB
Volume
72
Category
Article
ISSN
0007-1188

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3Z,6E)-l-Bromododeca-3,6-diene, a common intermediate in the synthesis of labelled 12t linoleic acid and 14t arachidonic acid, was obtained from (E)-3-nonyl-l-ol, in four steps, via conventional functional manipulations. Cross-coupling of this bromododecadiene with the Grignard reagent of l-chloro-5