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Arachidonic acid in astrocytes blocks Ca2+ oscillations by inhibiting store-operated Ca2+ entry, and causes delayed Ca2+ influx

✍ Scribed by Marina Sergeeva; Mikhail Strokin; Hong Wang; Joachim J. Ubl; Georg Reiser

Book ID
114117748
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
330 KB
Volume
33
Category
Article
ISSN
0143-4160

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## Abstract The effects of extracellular acidification on Ca^2+^‐dependent signaling pathways in human microglia were investigated using Ca^2+^‐sensitive fluorescence microscopy. Adenosine triphosphate (ATP) was used to elicit Ca^2+^ responses primarily dependent on the depletion of intracellular e