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Arachidonic Acid-Derived Bioactive Lipids: Their Role and the Role for Their Inhibitors in Dermatology

โœ Scribed by Kathleen J. Smith; Henry Skelton


Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
203 KB
Volume
6
Category
Article
ISSN
1203-4754

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The role of aspartic acid49 (Asp-49) in the active site of porcine pancreatic phospholipase A2 was studied by recombinant DNA techniques: two mutant proteins were constructed containing either glutamic acid (Glu) or lysine (Lys) at position 49. Enzymatic characterization indicated that the presence