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Arachidonic acid-dependent metabolism of (±) trans-7,8-dihydroxy-7,8- dihydro-benzo[a]pyrene (BP-7,8 diol) to 7,10/8,9 tetrols

✍ Scribed by Kandiah Sivarajah; Hasan Mukhtar; Thomas Eling

Book ID: 115909914
Publisher: Elsevier Science
Year: 1979
Tongue: English
Weight: 372 KB
Volume: 106
Category: Article
ISSN: 0014-5793
DOI: 10.1016/0014-5793(79)80685-7

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## Abstract trans‐7,8‐Dihydrobenzo[a]pyrene‐7,8‐diol‐7‐^14^C (VI) and (±)‐7α,8β‐dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo[a]‐pyrene‐7‐^14^C (VII) were prepared at a specific activity of 53.9 mCi/mmole by a multi‐step synthetic sequence using K^14^CN as the labeled precursor. The overall radio