Arachidonic Acid but not Eicosapentaenoic Acid (EPA) and Oleic Acid Activates NF-κB and Elevates ICAM-1 Expression in Caco-2 Cells

Catechols in caffeic acid phenethyl este

Catechols in caffeic acid phenethyl ester are essential for inhibition of TNF-mediated IP-10 expression through NF-κB-dependent but HO-1- and p38-independent mechanisms in mouse intestinal epithelial cells

✍ Job O. Mapesa; Nadine Waldschmitt; Ingrid Schmoeller; Carolin Blume; Thomas Hofm 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 335 KB

## Abstract **Scope**: Caffeic acid phenethyl ester (CAPE) is an active constituent of honeybee propolis inhibiting nuclear factor (NF)‐κB. The aims of our study were to provide new data on the functional relevance and mechanisms underlying the role of CAPE in regulating inflammatory processes at t