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Arachidonic acid activates a functional AP-1 and an inactive NF-κB complex in human HepG2 hepatoma cells

✍ Scribed by Philippe Bécuwe; Arnaud Bianchi; Céline Didelot; Muriel Barberi-Heyob; Michel Dauça

Book ID
114275664
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
381 KB
Volume
35
Category
Article
ISSN
0891-5849

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## Abstract Deoxycholic acid (DCA) has been implicated in colorectal carcinogenesis in humans with effects on proliferation and apoptosis, mediated at least in part by activation of transcription factors nuclear factor kappa B (NF‐κB), activator protein 1 (AP‐1) and protein kinase C (PKC) enzymes.