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Aqueous solubility of crystalline and amorphous drugs: Challenges in measurement

✍ Scribed by Murdande, Sharad B.; Pikal, Michael J.; Shanker, Ravi M.; Bogner, Robin H.

Book ID
120403482
Publisher
Informa plc
Year
2010
Tongue
English
Weight
910 KB
Volume
16
Category
Article
ISSN
1083-7450

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πŸ“œ SIMILAR VOLUMES

Drug–polymer solubility and miscibility:
Drug–polymer solubility and miscibility: Stability consideration and practical challenges in amorphous solid dispersion development
✍ Feng Qian; Jun Huang; Munir A. Hussain πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 131 KB

Drug-polymer solid dispersion has been demonstrated as a feasible approach to formulate poorly water-soluble drugs in the amorphous form, for the enhancement of dissolution rate and bioperformance. The solubility (for crystalline drug) and miscibility (for amorphous drug) in the polymer are directly