Aqueous humour and crystalline lens changes associated with ultraviolet radiation or mechanical damage to corneal epithelium in freshwater rainbow trout eyes
✍ Scribed by M.J. Doughty; A.P. Cullen; C.A. Monteith-McMaster
- Book ID
- 104373225
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 857 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1011-1344
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✦ Synopsis
In vivo irradiation of the eye of the rainbow trout with moderately high doses of UV-B (0.75 to 1.5 J cm -') can produce corneal danmge and persistent cataractous changes in the anterior part of the crystalline lens within hoP,rs. Irradiation with UV-C ( 0.25 J cm -2) also produces corneal damage but only temporary lens changes after 2-3 days. Cataractous changes can also occur following mechanical damage to the cornea ex vivo, and develop concurrently with decreases in the osmolarity of the aqueous humour of at least 30 mOsm ! ~; no change in aqueous humour osmolality was detected at the onset of cataracts associated with UVB irradiation in vivo. The UVB-associated anterior cataracts are thus not obviously caused by aqueou: humour changes although, when there is concurrent mechanical damage with the ultravio~t radiation, hypo-osmotic changes may contribute to the cataract formation.