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Aquaporin-4 deficiency down-regulates glutamate uptake and GLT-1 expression in astrocytes

✍ Scribed by Xiao-Ning Zeng; Xiu-Lan Sun; Lin Gao; Yi Fan; Jian-Hua Ding; Gang Hu

Book ID
116735479
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
546 KB
Volume
34
Category
Article
ISSN
1044-7431

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## Abstract Aquaporin‐4 (AQP4) is located on astrocyte endfeet that face blood vessels in the brain and in the pia. It is thought to play a crucial role in the development of brain edema. To confirm the notion that sex steroids and dexamethasone influence brain edema through AQP4 regulation, we inv