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Aquaporin-2 expression in the mammalian cochlea and investigation of its role in Meniere’s disease

✍ Scribed by Anand N Mhatre; Jussi Jero; Ilaria Chiappini; Giulia Bolasco; Maurizio Barbara; Anil K Lalwani

Book ID: 117534253
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 593 KB
Volume: 170
Category: Article
ISSN: 0378-5955
DOI: 10.1016/s0378-5955(02)00452-5

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## Abstract **Background:** Aquaporin 4 (AQP4) is a predominant water channel protein in mammalian brains, which is localized in the astrocyte plasma membrane. Membrane targeting of AQP4 is essential to perform its function. The mechanism(s) of membrane targeting is not clear in astrocytes. **Resu