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Aquaporin-1 Expression in Proximal Tubule Epithelial Cells of Human Kidney Is Regulated by Hyperosmolarity and Contrast Agents

โœ Scribed by Wheamei Jenq; Denise R. Cooper; Polly Bittle; German Ramirez


Book ID
115583417
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
486 KB
Volume
256
Category
Article
ISSN
0006-291X

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## Abstract Human proximal tubule (HKโ€2) cells are commonly used as cellular models to understand the mechanism by which inflammatory mediators cause renal injury. It has been observed that thrombin stimulates the expression of TGFโ€ฮฒ, extracellular matrix (ECM) proteins and proinflammatory cytokine