Aptatag-Based Multiplexed Assay for Protein Detection by Surface-Enhanced Raman Spectroscopy

✍ Scribed by Laura Fabris; Martin Schierhorn; Martin Moskovits; Guillermo C. Bazan

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 564 KB
• Volume: 6
• Category: Article
• ISSN: 1613-6810
• DOI: 10.1002/smll.201000262

✦ Synopsis

Abstract

Silver‐nanoparticle dimers held together by a Raman reporter, capped with DNA aptamers and stabilized by polyethylene glycol chains, can be used to develop a multiplexed heterogeneous bioassay for protein detection with high sensitivity and selectivity.