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Aptamer-Based Sensor Arrays for the Detection and Quantitation of Proteins

โœ Scribed by Kirby, Romy; Cho, Eun Jeong; Gehrke, Brian; Bayer, Travis; Park, Yoon Sok; Neikirk, Dean P.; McDevitt, John T.; Ellington, Andrew D.

Book ID
120394572
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
335 KB
Volume
76
Category
Article
ISSN
0003-2700

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Aptamer Beacons for the Direct Detection
Aptamer Beacons for the Direct Detection of Proteins
โœ Nobuko Hamaguchi; Andrew Ellington; Martin Stanton ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 148 KB

We have designed a new class of molecules, which we term aptamer beacons, for detecting a wide range of ligands. Similar to molecular beacons, aptamer beacons can adopt two or more conformations, one of which allows ligand binding. A fluorescence-quenching pair is used to report changes in conformat