Aptamer-Assembled Nanomaterials for Biosensing and Biomedical Applications

✍ Scribed by Rong-Mei Kong; Xiao-Bing Zhang; Zhuo Chen; Weihong Tan

• Book ID: 104593793
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 822 KB
• Volume: 7
• Category: Article
• ISSN: 1613-6810
• DOI: 10.1002/smll.201100250

✦ Synopsis

Aptamers represent a class of single-stranded DNA or RNA oligonucleotides that play important roles in biosensing and biomedical applications. However, aptamers can gain more fl exibility as molecular recognition tools by taking advantage of the unique chemical and physical properties provided by nanomaterials. Such aptamernanomaterial conjugates are having an increasing impact in the fi elds of biosensing, bioimaging, and therapy. The recent advances and limitations of aptamer-assembled nanomaterials in biosensing and biomedical applications are briefl y introduced and discussed.