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APRIL, a new member of the tumor necrosis factor family, modulates death ligand-induced apoptosis

โœ Scribed by Roth, W; Wagenknecht, B; Klumpp, A; Naumann, U; Hahne, M; Tschopp, J; Weller, M


Book ID
110016192
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
207 KB
Volume
8
Category
Article
ISSN
1350-9047

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Death-inducing functions of ligands of t
โœ David Wallach; Andrew V Kovalenko; Eugene E Varfolomeev; Mark P Boldin ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 992 KB

Members of the tumor necrosis factor ligand family can kill cells in a rather straightforward manner. They induce their receptors to recruit and activate caspases, enzymes that are critically involved in the death process, and this activation is further amplified by intracellular mitochondria-associ