## Synopsis Complexation of positively charged sites in a protein with the negative DNA phosphate groups shields the phosphate charges. This diminishes interstrand electrostatic repulsions, which stabilizes the duplex. When phosphate shielding is present in one DNA strand only, the conformation of
Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein
โ Scribed by Yasuteru Sano; Hidetoshi Date; Shuichi Igarashi; Osamu Onodera; Mutsuo Oyake; Toshiaki Takahashi; Shintaro Hayashi; Mitsunori Morimatsu; Hitoshi Takahashi; Takao Makifuchi; Nobuyoshi Fukuhara; Shoji Tsuji
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 770 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract To be of therapeutic relevance, a tumorโassociated antigen should be expressed on the surface of neoplastic cells but not, or to a significantly lower extent, on cells of nonโtransformed nature. The Ku heterodimer (Ku70/80) is involved in DNA double strand break recognition and repair a
The interaction of viral proteins with host-cellular proteins elicits the activation of numerous cellular signal transduction pathways possibly leading to the viral pathogenesis. We previously demonstrated that infection with Friend leukemia virus (FLV) radiosensitizes murine hematopoietic cells via
The protein dyes Light Green and Orange II were studied separately and in combination with the Feulgen-Pararosanilin(SO2) and -Thionin(SO2) method for the simultaneous determination of DNA and protein. - With polyacrylamide modelfilms the pH dependency, specificity and stoichiometry of Light Green a
## Abstract One of the forms of the insulinโlike growth factor (IGF) binding proteins present in human amniotic fluid has been shown to potentiate the growthโpromoting effect of IGFโI markedly. This study was undertaken to determine the cellular and hormonal factors that modulate this potentiation