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Approaches to the Synthesis of Cytochalasans. Part 2. Pyrrolinone derivatives as basic units

✍ Scribed by Tibur Schmidlin; Christoph Tamm

Publisher
John Wiley and Sons
Year
1980
Tongue
German
Weight
632 KB
Volume
63
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Several attempts to prepare 3‐acetyl‐5‐benzyl‐3‐pyrrolin‐2‐one (7) from phenylalanine are described. This goal was only reached formally, because compound 7 exists in the tautomeric form of (Z)‐5‐benzyl‐3‐(1′‐hydroxyethylidene)‐4‐pyrrolin‐2‐one (17) according to the spectral data. The problem of tautomerism in pyrrolinone systems is discussed.

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