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Approaches to the design of selective ligands for membrane progesterone receptor alpha

✍ Scribed by Lisanova, O. V.; Shchelkunova, T. A.; Morozov, I. A.; Rubtsov, P. M.; Levina, I. S.; Kulikova, L. E.; Smirnov, A. N.


Book ID
120026663
Publisher
Springer
Year
2013
Tongue
English
Weight
171 KB
Volume
78
Category
Article
ISSN
0006-2979

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An analytical method is described whereby progesterone is isolated from pregnancy plasma on the basis of the high affinity and specificity of the progesterone receptor for its ligand. Partially purified progesterone receptor ligand-binding domain, expressed as a protein A fusion protein in Escherich