Approach towards the total synthesis of cyclopeptide alkaloids

✍ Scribed by Taoues Laïb; Jieping Zhu

• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 243 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)10513-5

✦ Synopsis

Macrocylization via formation of aryl-alkyl ether bond was a key step in a model synthesis of 14-membered cyclopeptide alkaloids. A new chemoenzymadc synthesis of chiral 2amino-l-arylethanol was developed in the course of this study