Approach to the synthesis of nogalarol via the cycloaddition of a carbene-chromium complex with a functionalized alkyne
โ Scribed by M.F. Semmelhack; Nakcheol Jeong
- Book ID
- 108382484
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 318 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
The development of a synthetic approach to the fredericamycin A ABCDE ring system based on a regiospecijic intermolecular alkyne-chromium carbene complex cyclization is detailed.
## Examination of a steric and electronic factor of alkyne in regioselectivity in the reaction of a phenyl chromium carbene complex with unsymmetrical alkynes is described.
Described is the preparation of cyclobutanones via the [2+2]-cycloaddition of ketenes with olefins and the photolytic reaction of chromium-carbene complexes with olefins and dienes. A comparison of these two methods is reported.