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Applications of Raman spectroscopy to ophthalmology: Spectroscopic characterization of disposable soft contact lenses

✍ Scribed by P. Monti; R. Simoni; R. Caramazza; A. Bertoluzza

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 155 KB
Volume: 4
Category: Article
ISSN: 1075-4261
DOI: 10.1002/(sici)1520-6343(1998)4:6<413::aid-bspy6>3.0.co;2-g

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✦ Synopsis

Disposable soft contact lenses based on HEMA-MAA hydrogels are examined using Raman and ATR/FTIR vibrational spectroscopies and thermal analysis. The main factors dealing with physical, chemical, and biological biocompatibility are evaluated in relation to those of long-wear soft contact lenses with the aim of individuating the most biocompatible lens. The Raman spectra of HEMA-MAA lenses show that some biocompatibility factors are affected by environmental conditions and, in particular, by changes in pH and ionic strength values.

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