## Abstract In most enzymatic reactions, batch or continuous, separation of the enzyme for reuse is difficult if not impossible. A process will be presented in which an Ultrafiltration membrane serves to separate the reaction products from the enzyme and the substrate. In this manner the enzyme may
Applications of purification reactions for minimizing reaction-generated enzyme poisoniong
β Scribed by Simon Y. S. Yeung; Yong K. Cho; James E. Bailey
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 708 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0006-3592
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β¦ Synopsis
Abstract
A mathematical model has been employed to examine the interplay of reaction and mass transfer in immobilized enzyme systems involving reactionβgenerated enzyme poisons. Deactivation rates can be significantly reduced in some cases by catalyzing a purification reaction in which the poison is transformed into an innocuous substance. This conclusion is illustrated experimentally for reactionβgenerated H~2~O~2~ in a continuousβflow stirred slurry reactor containing glucose oxidase immobilized on activated carbon.
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