Applications of differential scanning calorimetry in pharmaceutical analysis

✍ Scribed by Renate Reubke; Joseph A. Mollica Jr.

• Publisher: John Wiley and Sons
• Year: 1967
• Tongue: English
• Weight: 361 KB
• Volume: 56
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600560706

✦ Synopsis

The application of differential scanning calorimetry to several aspects of pharmaceutical analysis is presented. These include the utilization of this technique in the quantitative estimation of purity, in the relative determination of purity for a control procedure, and in the detection of polymorphism. The purities and heats of fusion of diallylbarbituric acid, naphthalene, glutethimide, dibucaine, and anthraquinone are given. A comparative analysis of several samples of methyl reserpate is presented and the detection of polymorphism in tripelennamine citrate is discussed.