A direct stereocontrolled route for the construction of highly substituted cyclopentanones 10a-d has been developed starting from aeyclic ketones 5a,b. The key step involves copper(I)-eatalysed stezeoselective photocycloaddition of the dienes 6a-d followed by stereospecific rearrangement of the cycl
β¦ LIBER β¦
Applications of cyclopropylboranes in organic synthesis. 1. A stereocontrolled route to substituted cyclopropanol derivatives
β Scribed by Danheiser, Rick L.; Savoca, Ann C.
- Book ID
- 126898370
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 386 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
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## Abstract An efficient synthesis of enaminones **1aβc** is reported. Compounds **1aβc** reacted with diefhylβ3βaminoβ2βcyanopentenβ1,5βdicarboxylate (**3**) to yield the benzonitriles **6**. On the other hand, the reaction of **laβc** with 3βaminoβ2βcyanoβ2βpentene dinitrile (**7**) afforded a mi