Applications of collagenolytic protease preparations from invertebrates
โ Scribed by O. A. Klimova; V. Yu. Chebotarev
- Book ID
- 105573647
- Publisher
- Springer US
- Year
- 1999
- Tongue
- English
- Weight
- 281 KB
- Volume
- 128
- Category
- Article
- ISSN
- 0007-4888
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Collagenolytic protease I from the fiddler crab Uca pugilator belongs to the serine proteases of the trypsin family. A graphic molecular model was built using information from sequences and X-ray structures of four homologous proteins which were superimposed to define structurally conserved regions.
The debriding activity of the protease complex produced from the hepatopancreas of the king crab Paralirhodes camtschatica was evaluated in vivo. The results clearly showed that the crab preparation had a high debriding ability. Individual proteases were isolated chromatographically from the crab co