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Application of xanthine oxidase-catalyzed luminol chemiluminescence in a mouse interleukin-5 immunoassay

✍ Scribed by H.A.H. Rongen; H.M. van der Horst; A.J.M. van Oosterhout; A. Bult; W.P. van Bennekom


Book ID
113181970
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
807 KB
Volume
197
Category
Article
ISSN
0022-1759

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The use of xanthine oxidase (XO) as a label in immunoanalysis has not been previously reported. This can be explained by the difficulties encountered in XO assays (poor sensitivity and versatility) and the competitive inhibition of the enzyme by allopurinol, a widely used hypouricemic agent. We demo