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Application of the Goldilocks Effect to the Design of Potent and Selective Inhibitors of Phenylethanolamine N -Methyltransferase: Balancing p K a and Steric Effects in the Optimization of 3-Methyl-1,2,3,4-tetrahydroisoquinoline Inhibitors by β-Fluorination 1

✍ Scribed by Grunewald, Gary L.; Seim, Mitchell R.; Lu, Jian; Makboul, Mariam; Criscione, Kevin R.


Book ID
118183005
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
327 KB
Volume
49
Category
Article
ISSN
0022-2623

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