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Application of the DNA adductome approach to assess the DNA-damaging capability of in vitro micronucleus test-positive compounds

✍ Scribed by Kyoko Kato; Eiji Yamamura; Masanobu Kawanishi; Takashi Yagi; Tomonari Matsuda; Akio Sugiyama; Yoshifumi Uno


Book ID
116759872
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
485 KB
Volume
721
Category
Article
ISSN
1383-5718

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## Abstract The mutagenic and carcinogenic effects of genotoxic agents on exposed people have constituted an increasing concern. Therefore, the objective of this work was to assess DNA damage in lymphocytes of workers exposed to X‐radiation using the cytokinesis‐blocked micronucleus test and the co