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Application of the asymmetric chelate-enolate claise rearrangement to the synthesis of 5-epi-isofagomine

✍ Scribed by Uli Kazmaier; Christiane Schneider


Book ID
104258699
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
122 KB
Volume
39
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


Application of the Chelate-Enolate Clais
✍ Kazmaier, Uli πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 1000 KB

## Abstract Deprotonation of __N__‐protected amino acid allylic esters with LDA at βˆ’78Β°C and subsequent addition of a metal salt presumably results in the formation of a chelated metal enolate that undergoes Claisen rearrangement upon warming up to room temperature, giving rise to __Ξ³,Ξ΄__‐unsaturat