✦ LIBER ✦

Application of Terahertz Time-Domain Spectroscopy in Intracellular Metabolite Detection

✍ Scribed by Changlei Wang; Jixian Gong; Qirong Xing; Yanfeng Li; Feng Liu; Xueming Zhao; Lu Chai; Chingyue Wang; Aleksei M. Zheltikov

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 251 KB
Volume: 3
Category: Article
ISSN: 1864-063X
DOI: 10.1002/jbio.201000043

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✦ Synopsis

Abstract

Using terahertz time‐domain spectroscopy (THz‐TDS), we have investigated the THz spectra of astaxanthin and riboflavin and the spectra of two kinds of cell, haenatcoccus plusivalis and bacillus subtilis, which could produce astaxanthin and riboflavin, respectively, during their metabolite process. Riboflavin was found to be much more absorptive to THz radiation and have richer spectral characteristics than astaxanthin. As an intracellular metabolite, riboflavin could be distinguished from the cells by using THz‐TDS. The technique has potential applications in high‐throughput screening of industrial strains. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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