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Application of Organolithium Compounds in Organic Synthesis. XIX. Synthetic Strategies Based on Aromatic Metallation. A Concise Regiospecific Synthesis of 3-Halogenated Picolinic and Isonicotinic Acids

✍ Scribed by Epsztajn, J.; Płtka, M. W.; Grabowska, A.


Book ID
120599826
Publisher
Taylor and Francis Group
Year
1997
Tongue
English
Weight
378 KB
Volume
27
Category
Article
ISSN
0039-7911

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Dedicated with admiration and a]j'ktion, to Alan R. Katritzky on his 63th birthday Absbod: The synthesis o/the 3-hy~~-3-~ri~l-isotndolin-l-onEs (5) and (6) via metallation (n-BuLt) of the benzanilides (I), and then the reaction of the generated bis lithinted anilides (2) with N,N-dimet&lamides or me