An on-line method has been developed for the derivatization and coupled liquid chromatography (LC)/electrospray ionization (ESI) MS analysis of peptides at the femtomol level. Peptides are reacted with N-succinimidyl-2(3-pyridyl)acetate (SPA) in buffered aqueous medium at pH 7 following loading on a
Application of On-Line Electrochemical Derivatization Coupled with High-Performance Liquid Chromatography Electrospray Ionization Mass Spectrometry for Detection and Quantitation of ( p -Chlorophenyl)aniline in Biological Samples
β Scribed by Chen, Hao; Zhang, Yanhua; Mutlib, Abdul E.; Zhong, Min
- Book ID
- 127085096
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 137 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0003-2700
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