Application of a generic fast gradient l
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J. Ayrton; R. Plumb; W. J. Leavens; D. Mallett; M. Dickins; G. J. Dear
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Article
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1998
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John Wiley and Sons
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English
โ 194 KB
๐ 2 views
A liquid chromatography tandem mass spectrometry (LC/MS/MS) method has been developed for the fast routine analysis of selected CYP450 probe substrate metabolites in microsomal incubations, with no sample pretreatment. This has allowed fast and simple assessment of the potential effects which drug c