Application of mineral support on cephamycin C production in culture using soybean oil as the sole carbon source
✍ Scribed by Ichida Mitsuru; Yong Soo Park; Yuko Kosakai; Mitsuyasu Okabe
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 398 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0006-3592
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✦ Synopsis
A mineral support was used for cephamycin C production in a culture using soybean oil as the sole carbon source. When the support was added into an oil-water system, the soybean oil was emulsified as fine oil droplets, which was observed by a photomicroscope. Mycelia were also twined around the support, which was observed by a scanning electron microscope. That caused the formation of an oil-mycelia complex on or around the support, which provided a larger specific surface area of oil. When 15 g/L of the support was used in a batch culture of Streptomyces sp. P6621 with 50 g/L of soybean oil, the maximum cephamycin C concentration was 2.8 g/L, which was 2.2 times higher than that without the support. This indicates that the mineral support is useful for the culture system using vegetable oil as a carbon source.