Application of mass spectrometry to structure problems: the occurrence of eburnamenine and related alkaloids in Rhazya stricta and Aspidosperma quebracho blanco

✍ Scribed by H.K. Schnoes; A.L. Burlingame; K. Biemann

• Publisher: Elsevier Science
• Year: 1962
• Tongue: French
• Weight: 299 KB
• Volume: 3
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)70945-2

✦ Synopsis

The leaves of Rhazya stricta Decaisne are reported' to coutain akuammidine I (= rhazine): and quebrachamine (II),4 one of the major alkaloids of ASD~~OSPSOS auebracho blanco. Recently we had investigated the alkaloids of quebracho bark which led to the discovery of a number of new alka1oids.s It was thus of interest to search other quebrachamine-producing plants for these aspidospermr alkaloids and we therefore extracted a small sample (we had only 11 g. at out disposal) of the leaves of Rhazya stricta and examined the less polar base-fractions.

Gas chFamrtographic separation of the crude alkaloid mixture led to several fractions, the mass spectra of which indicated that there aret in IFartIK.