Application of Liposome-Entrapped Drugs
β Scribed by Hisashi Kumashiro; Norio Mori; Toshihiko Fukatsu; Takashi Sato
- Book ID
- 118708050
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 130 KB
- Volume
- 40
- Category
- Article
- ISSN
- 1323-1316
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π SIMILAR VOLUMES
Liposomes are non-toxic, biodegradable and feebly immunogenic lipid vesicles made from natural and synthetic lipids. They are known to act as immunopotentiating agents and can be used to formulate sustained release preparation by encapsulation. In the present study, liposome entrapped allergen and f
Floxuridine was found to have an apparent initial entrapment within negatively charged sphingomyelin liposomes about three times higher than its parent, fluorouracil. The drug also diffused out of the liposomes at a much lower rate than fluorouracil. Substitution of lecithin for sphingomyelin destro