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Application of LC-MS to the analysis of new radiopharmaceuticals

โœ Scribed by Ying Ma; Dale Kiesewetter; Lixin Lang; William C Eckelman


Book ID
116747889
Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
137 KB
Volume
5
Category
Article
ISSN
1536-1632

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This article describes the application of liquid chromatography combined with mass-spectrometry (LC-MS) as a new quality control tool for PET-radiopharmaceuticals. The final step in the production of 2-[Vjfluoro-2deoxy-o-glucose ( 18F-FDG) is a purification by HPLC. This procedure was validated by